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ACID RESISTANT CAPSULES

An acid resistant capsule comprises at least one hard capsule shell, said shell comprising: an enteric polymer having acid groups; a film-forming aid; and an alkaline material, wherein said alkaline material is present in an amount such that said carboxylic acid groups of said enteric polymer have a degree of ionization of less than 15%.

Last Updated: 01/26/2018 - 7:10am

LIPID FORMULATIONS CONTAINING BIOACTIVE FATTY ACIDS AND OTHER BIOACTIVE AGENTS

Provided herein is technology relating to compositions containing bioactive non-methylene interrupted fatty acids (NMIFAs) in combination with short chain fatty acids, medium chain fatty acids, ketone bodies and/or endocannabinoids and endocannabinoid-related mediators, and particularly, but not exclusively, to compositions and methods related to the production and use of non-methylene interrupted fatty acids such as sciadonic acids, juniperonic acid, pinoleic acid and dihomopinoleic acid in combination with short chain fatty acids, medium chain fatty acids and/or endocannabinoids and endoc

Last Updated: 01/26/2018 - 7:10am

SULFONYLCYCLOALKYL CARBOXAMIDE COMPOUNDS AS TRPA1 MODULATORS

The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

Last Updated: 01/26/2018 - 7:03am

BICYCLIC PROLINE COMPOUNDS

The invention is concerned with the compounds of formula (I) and salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

Last Updated: 01/26/2018 - 7:03am

NOVEL [1,2,31TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES

The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

Last Updated: 01/26/2018 - 7:03am

PROCESS AND EXTRUSION DIE HEAD FOR FORMING A DIVIDED CONDUIT

A process for extruding a divided conduit (400) comprising obtaining an extrusion die head (10), inserting a strip-shaped substrate (300) into the extrusion die head (10) such that the strip shaped substrate (300) is located within the tip gap (150) and extends at least partially out of the tip gap (150) such that the longitudinal edges are located in the die gap (250), and flowing molten polymer through die gap (250), encapsulating the longitudinal edges of the strip-shaped substrate (300) in molten polymer. The extrusion die head (10) contains a tip (110) region and a bushing (200).

Last Updated: 01/26/2018 - 4:31am

SHAPED VITRIFIED ABRASIVE AGGLOMERATE, ABRASIVE ARTICLES, AND METHOD OF ABRADING

An abrasive agglomerate particle includes fused aluminum oxide mineral bonded in a vitreous matrix. The fused aluminum oxide mineral is present in a range from 70 percent by weight to 95 percent by weight and the vitreous matrix is present at least at five percent by weight, based on the weight of the abrasive agglomerate particle.

Last Updated: 01/26/2018 - 4:31am

PROCESS FOR PROVIDING ANTIMICROBIAL TREATMENT TO NOV-WOVEN FABRICS

An apparatus and process for disinfecting, and, optionally, sterilizing, fibers and non-woven materials produced from the fibers is disclosed, as well as processes for converting fibers into disinfected and/or sterilized non-woven materials. The process involves contacting the fibers and/or non-woven materials with high temperature steam, and then with UV light, which is preferably UV-C light, or another disinfectant process, such as ozone treatment.

Last Updated: 01/26/2018 - 4:31am

SYSTEMS AND METHODS FOR PREPARING AND CO-PROCESSING BIOCRUDE OIL

The present application generally relates to catalytically preparing liquid fuel products with an improved product mix by co-processing a plurality of reactants in in refinery or field- upgrading operations. The reactants may include, for example, petroleum fraction and a biocrude oil having an alcohol additive.

Last Updated: 01/26/2018 - 4:31am

AMMONIA OXIDIZING MICROORGANISMS FOR USE AND DELIVERY TO THE GASTROINTESTINAL SYSTEM

Ammonia oxidizing microorganism preparations for delivery to the gastrointestinal system, kits including ammonia oxidizing preparations for delivery to the gastrointestinal system, and devices for administering ammonia oxidizing preparations to the gastrointestinal system are provided. Methods of introducing ammonia oxidizing microorganisms to the gastrointestinal system are provided. Methods of treating disorders, including gastrointestinal disorders and inflammatory disorders, with ammonia oxidizing microorganism preparations are provided.

Last Updated: 01/26/2018 - 4:31am

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